The sensitivity of the myocardium to alterations in its electrolyte environment has been extensively studied. Danowski and Elkinton (1951) in a detailed review on the effects of potassium on the functions of various organs and systems of the body conclude that "the heart is the most sensitive of all organs to alterations in its extracellular potassium concentration." It is now well established that the concentration of potassium in the extra cellular fluid is low (4 to 5 mEq. per liter in plasma) while the intracellular concentration is considerably higher--approximately 40 mEq. per 100 grams of cat heart tissue (Robertson and Peyser, 1951)
The effects of quinidine and its interactions with potassium (K) on atrio-ventricular (A-V) conducti...
This investigation tested the hypothesis that uptake of potassium during respiratory acidosis is sec...
"When the potassium is injected slowly, after a time the heart gradually slows to perhaps half ...
One current concept of the action of the carclio-active glycosides is based on experiments which sho...
SUMMARY The median single pulse ventricular fibrillation threshold of 56 determinations in eight iso...
effects of K+, acidosis, and catecholamines on isolated rabbit heart: implications for exercise. J. ...
1. The effects of a decrease of the K gradient on the extraneuronal inward transport and outward mov...
In the extensive literature on the action of epinephrin, a number of communications may be found dea...
Szent-Gyorgyi has demonstrated the importance of the 'intracellular ionic atmosphere' on the contrac...
The force and general behaviour of cardiac con-traction can be altered in striking fashion under exp...
Although it is generally recognized that digi-talis-induced arrhythmias can be suppressed by the adm...
THE RELATION of cationic distributionto the tonus of vascular smooth muscle has become of increasing...
The work to be reported in this paper was begun on the basis of two comi-siderations. The first is t...
That the hydrogen-ion concentration of the fluids bathing the cell plays an important role in the pr...
Increases in extracellular potassium (K+) concentration (up to 20 mM) cause dilation in some blood v...
The effects of quinidine and its interactions with potassium (K) on atrio-ventricular (A-V) conducti...
This investigation tested the hypothesis that uptake of potassium during respiratory acidosis is sec...
"When the potassium is injected slowly, after a time the heart gradually slows to perhaps half ...
One current concept of the action of the carclio-active glycosides is based on experiments which sho...
SUMMARY The median single pulse ventricular fibrillation threshold of 56 determinations in eight iso...
effects of K+, acidosis, and catecholamines on isolated rabbit heart: implications for exercise. J. ...
1. The effects of a decrease of the K gradient on the extraneuronal inward transport and outward mov...
In the extensive literature on the action of epinephrin, a number of communications may be found dea...
Szent-Gyorgyi has demonstrated the importance of the 'intracellular ionic atmosphere' on the contrac...
The force and general behaviour of cardiac con-traction can be altered in striking fashion under exp...
Although it is generally recognized that digi-talis-induced arrhythmias can be suppressed by the adm...
THE RELATION of cationic distributionto the tonus of vascular smooth muscle has become of increasing...
The work to be reported in this paper was begun on the basis of two comi-siderations. The first is t...
That the hydrogen-ion concentration of the fluids bathing the cell plays an important role in the pr...
Increases in extracellular potassium (K+) concentration (up to 20 mM) cause dilation in some blood v...
The effects of quinidine and its interactions with potassium (K) on atrio-ventricular (A-V) conducti...
This investigation tested the hypothesis that uptake of potassium during respiratory acidosis is sec...
"When the potassium is injected slowly, after a time the heart gradually slows to perhaps half ...