More than two centuries have elapsed since the first isolation of cholesterol, yet its structure was elucidated only twenty-two years ago and its total synthesis was achieved in 1951. The first steroid hormone to be isolated in pure state was estrone in 1929. Within a short period of time the various sex hormones, estrogens, androgens and progestins were isolated, characterized and synthesized. The compounds elaborated by the adrenal cortex were the last type of steroid hormones to be investigated. Experiments initiated in 1935 led to the isolation and characterization of twenty-eight crystalline steroids, six of which exhibit activity in prolonging the life of adrenalectomized animals
A large number of 17-ketosteroids have been found in the urine since the first one vas isolated almo...
Preliminary studies on the biosynthesis of steroids by the rat adrenal using radioactive precursors ...
The first half of the 20th century was marked by significant scientific advances in the study of hor...
Significant chemical work on the hormones of the adrenal cortex dates from 1930 when Swingle and Pfi...
A quarter of a century has elapsed since the first steroid hormone was isolated. Since then, there h...
Thirty years of intensive research have demonstrated the importance of the physiological role played...
The compound now known as cholesterol was first isolated by Poulletier de la Salle in 1770. The eluc...
Hormones are classified according to their physiological actions rather than by their chemical struc...
The fundamental discovery by investigators at the Worcester Foundation that perfused bovine adrenals...
Replacement therapy provided the first element of knowledge of the nature of adrenocortical secretio...
The study of steroid metabolism began in the eighteenth century with the demonstration of the presen...
The biochemistry of the steroid hormones continues to engage the efforts of a large number or resear...
More than thirty years ago estrone, the first hormonally active steroid, was isolated from human pre...
In 1943, Vogt (l) was able to show that the adrenal venous blood of animals contained a high concent...
RANSFORAMTIONS of steroids have been the object of intensive study in bio-logical systems of varying...
A large number of 17-ketosteroids have been found in the urine since the first one vas isolated almo...
Preliminary studies on the biosynthesis of steroids by the rat adrenal using radioactive precursors ...
The first half of the 20th century was marked by significant scientific advances in the study of hor...
Significant chemical work on the hormones of the adrenal cortex dates from 1930 when Swingle and Pfi...
A quarter of a century has elapsed since the first steroid hormone was isolated. Since then, there h...
Thirty years of intensive research have demonstrated the importance of the physiological role played...
The compound now known as cholesterol was first isolated by Poulletier de la Salle in 1770. The eluc...
Hormones are classified according to their physiological actions rather than by their chemical struc...
The fundamental discovery by investigators at the Worcester Foundation that perfused bovine adrenals...
Replacement therapy provided the first element of knowledge of the nature of adrenocortical secretio...
The study of steroid metabolism began in the eighteenth century with the demonstration of the presen...
The biochemistry of the steroid hormones continues to engage the efforts of a large number or resear...
More than thirty years ago estrone, the first hormonally active steroid, was isolated from human pre...
In 1943, Vogt (l) was able to show that the adrenal venous blood of animals contained a high concent...
RANSFORAMTIONS of steroids have been the object of intensive study in bio-logical systems of varying...
A large number of 17-ketosteroids have been found in the urine since the first one vas isolated almo...
Preliminary studies on the biosynthesis of steroids by the rat adrenal using radioactive precursors ...
The first half of the 20th century was marked by significant scientific advances in the study of hor...