International audienceShadoo and PrP belongs to the same protein family, whose biological function remains poorly understood. Previous experiments reported potential functional redundancies or antagonisms between these two proteins, depending on the tissue analysed. While knockdown experiments suggested the requirement of Shadoo in the absence of PrP during early mouse embryogenesis, knockout ones, on the contrary, highlighted little impact, if any, of the double-knockout of these two loci. In the present study, we reinvestigated the phenotype associated with the concomitant knockout of these two genes using newly produced FVB/N Sprn knockout mice. In this genetic background, the combined two genes & rsquo; knockout induces intra-uterine gr...
AbstractThe prion protein PrP has a key role in transmissible spongiform encephalopathies but its bi...
The potential requirement of either the Prion or Shadoo protein for early mouse embryogenesis was re...
Based on its developmental pattern of expression, early studies suggested the implication of the mam...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceThe Shadoo and PrP prion protein family members are thought to be functionally...
International audienceThe Shadoo and PrP prion protein family members are thought to be functionally...
<div><p>The potential requirement of either the Prion or Shadoo protein for early mouse embryogenesi...
AbstractThe prion protein PrP has a key role in transmissible spongiform encephalopathies but its bi...
The potential requirement of either the Prion or Shadoo protein for early mouse embryogenesis was re...
Based on its developmental pattern of expression, early studies suggested the implication of the mam...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceShadoo belongs to the prion protein family, an evolutionary conserved and exte...
International audienceThe Shadoo and PrP prion protein family members are thought to be functionally...
International audienceThe Shadoo and PrP prion protein family members are thought to be functionally...
<div><p>The potential requirement of either the Prion or Shadoo protein for early mouse embryogenesi...
AbstractThe prion protein PrP has a key role in transmissible spongiform encephalopathies but its bi...
The potential requirement of either the Prion or Shadoo protein for early mouse embryogenesis was re...
Based on its developmental pattern of expression, early studies suggested the implication of the mam...