This paper presents a demonstration setup for live HEVC video coding with Region of Interest (ROI) encryption. The showcased approach splits video frames into independent HEVC tiles and encrypts those belonging to the ROI. This end-to-end content protection scheme is put into practice by integrating the algorithms of selective encryption into Kvazaar HEVC encoder and decryption into openHEVC decoder. The shown implementation performs secure encryption of the ROI in real time with small bit rate and complexity overhead.Peer reviewe