GROWTH PERFORMANCE AND HISTOLOGICAL APPEARANCE OF THE HUMPBACK GROUPER JUVENILE (CROMILEPTESALTIVELIS) AFTER TREATED WITH RECOMBINANT GROWTH HORMONE

Despite as high price consumption fish, humpback grouper grow out take very long time so its culture considered not efficient. Therefore to accelerate its growth rate and make grow out culture more efficient, recombinant Epinepheluslanceolatus growth hormone (rElGH) was applied by oral route. Daily application of rough rElGH at a dose of 5 mg/100 g commercial diet for 42 days resulted significance increase in growth rate compared to control groups. No specific histological damage on kidney, liver and spleen which was attributable to rElGH administration. These results strongly suggested that growth stimulation following oral administration was due to a specific action of rElGH and recombinant GH as mentioned above save for fish consumption. Keywords: growth, histology, humpback grouper, recombinant growth hormone