The properties of the biotin-streptavidin sensor system such as surface topology, regeneration of probes and non-specific interaction effects are investigated in detail by using DNA-DNA hybridization interactions as the test system. Surface Plasmon Resonance (SPR) and SPR enhanced fluorescence spectroscopy (SPRFS) detection schemes were widely employed to monitor the effect of probe/target length, mismatches and temperature on the hybridization kinetics. 1:1 Langmuir kinetic models were found to be sufficient to describe the hybridization interactions
The surface conformation and accessibility of oligonucleotides within arrays are two key parameters ...
Summary Biosensors have been successfully applied to study DNA hybridization reactions for several y...
We report on the development of a new platform technology for the detection of genetic variations by...
The properties of the biotin-streptavidin sensor system such as surface topology, regeneration of pr...
[[abstract]]In the past few years, gene therapy, genetic modification and other related issues are t...
We have demonstrated a simple yet direct method for determining the kinetic parameters in DNA-DNA in...
Since we observed that dendron-assembled surface provided high single nucleotide polymorphism discri...
Semisynthetic, covalent streptavidin-DNA adducts are versatile molecular connectors for the fabricat...
Three multi-step multi-molecular approaches using the biotin–streptavidin system to contact-print DN...
In this paper we present a fiber optic surface plasmon resonance (SPR) sensor as a reusable, cost-ef...
AbstractSurface plasmon field-enhanced fluorescence spectroscopy was employed to extensively investi...
BACKGROUND: The recent development of biosensor technologies for biospecific interaction analysis en...
Surface plasmon resonance (SPR) biosensors represent one of the most advanced sensing technologies f...
We report the investigation of biotin-streptavidin binding interactions using microcantilever sensor...
In this paper a fiber optic surface plasmon resonance (FO-SPR) sensor was used to analyze the meltin...
The surface conformation and accessibility of oligonucleotides within arrays are two key parameters ...
Summary Biosensors have been successfully applied to study DNA hybridization reactions for several y...
We report on the development of a new platform technology for the detection of genetic variations by...
The properties of the biotin-streptavidin sensor system such as surface topology, regeneration of pr...
[[abstract]]In the past few years, gene therapy, genetic modification and other related issues are t...
We have demonstrated a simple yet direct method for determining the kinetic parameters in DNA-DNA in...
Since we observed that dendron-assembled surface provided high single nucleotide polymorphism discri...
Semisynthetic, covalent streptavidin-DNA adducts are versatile molecular connectors for the fabricat...
Three multi-step multi-molecular approaches using the biotin–streptavidin system to contact-print DN...
In this paper we present a fiber optic surface plasmon resonance (SPR) sensor as a reusable, cost-ef...
AbstractSurface plasmon field-enhanced fluorescence spectroscopy was employed to extensively investi...
BACKGROUND: The recent development of biosensor technologies for biospecific interaction analysis en...
Surface plasmon resonance (SPR) biosensors represent one of the most advanced sensing technologies f...
We report the investigation of biotin-streptavidin binding interactions using microcantilever sensor...
In this paper a fiber optic surface plasmon resonance (FO-SPR) sensor was used to analyze the meltin...
The surface conformation and accessibility of oligonucleotides within arrays are two key parameters ...
Summary Biosensors have been successfully applied to study DNA hybridization reactions for several y...
We report on the development of a new platform technology for the detection of genetic variations by...