Investigations of Azulene Derivatives as Self-Indicating Chromophores for Applications in Protecting Group Strategies and Solid-Phase Purification

Azulene is a hydrocarbon that exhibits an intense blue colour. Derivatives of azulene exhibit different colours depending on the position and electronic properties of the substituents. The chemical and chromophoric properties of azulene and guaiazulene derivatives are investigated for the potential use in applications such as chromophoric protecting groups and self-indicating scavenger resins. Investigations were carried out on the scope of known reactions on the 3- position of guaiazulene for this purpose..