According to EEA (European Environmental Agency), flood is the most dangerous natural hazard in Europe in terms of economic losses. TheKULTURisk Project (EU FP7) has developed a novel methodology for evaluating the integrated benefits of risk prevention of water related natural hazards: SERRA (i.e. Socio-Economic Regional Risk Assessment). The proposed methodology enhances the traditional flood risk assessment by integrating the missing socio-economic dimension into the established regional risk assessment. Several case studies across Europe allowed for the consolidation, validation, and refinement of SERRA. This paper presents the results of its application to assess the benefits deriving from the installation of an Early Warning System in...