Srovnani trough/peak pomeru kardioselektivnich betablokatoru u pacientu s cerstve zjistenou hypertenzi.

Hypertension is an important risk factor for cardiovascular disease. One of the major characteristic features of the new antihypertensive drugs is their 24-hour effectiveness. If the drug reaches the mean trough/peak ratio over 50%, it can be dosed once a day. Beta-blockers are one of initial drug choice in young patients with hypertension. The objectives of the study were to compare T/P ratios of slow-release betaxolole and metaprolol using 24-hour blood pressure monitoring in patients with newly diagnosed hypertension, to evaluate its 24-hour and office efficacy in blood pressure lowering and to review diurnal rhythm changes after the treatment (dippers contra nondippers).Available from STL Prague, CZ / NTK - National Technical LibrarySIGLECZCzech Republi