Vyskyt mykobakterialnich onemocneni u nekalmetizovanych deti.

The subject of the thesis is a prospective study of mycobacterial infections in children. The aims of the study were: - to ascertain the incidence of mycobacterial diseases in BCG vaccinated and BCG non vaccinated children, - to compare the risk of mycobacterial diseases in BCG vaccinated and BCG non vaccinated children, - to evaluate the clinical status and laboratory levels in tuberculous and nontuberculous mycobacterial disease. The risk of tuberculosis in children between 1-8 years of age in BCG non vaccinated and BCG vaccinated cohort is not statistically significant. The risk of nontuberculous avian mycobacteriosis is significantly higher in BCG non vaccinated cohort. BCG immunization in newborns significantly protects children between 0-8 years of age against Mycobacterium avium disease. BCG non vaccinated children between 1-5 years of age are the most endangered group for these infections. The occurrence of nontuberculous avian lymphadenitis in BCG non vaccinated children is comparable to the occurrence of regional BCG lymphadenitis in children vaccinated in newborn age.Summary in EnglishAvailable from STL, Prague, CZ / NTK - National Technical LibrarySIGLECZCzech Republi