Prinos krevni kardioplegie pro ochranu myokardu pri aortokoronarnim bypassu u nemocnych s dysfunkci leve komory srdecni.

This study was done to compare the protective effect of blood and crystalloid cardioplegia in patients with left ventricular dysfunction with a view to the changes during early postoperative phase. All patients in this study were operated under general anaesthesia by the use of cardiopulmonary bypass. In both groups moderate systemic hypothermia and topical hypothermia were used. Internal mammary artery bypasses were implanted as last anastomoses. We can summarise that we didnt find significant differences in mortality, perioperative myocardial infarction rate and need of mechanical heart support in postoperative myocardial infarction rate and need of mechanical heart support in postoperative period between blood and crystalloid cardioplegia groups. The cardiospecific enzyme response was significantly lower in the blood cardioplegia group and the LVSW and LVSWI was significantly higher in the blood cardioplegia group one hour after operation. We conclude. that blood cardioplegia shows earlier improvement of myocardial function after the operation. Blood cardioplegia could be beneficial in patients with severe left ventricular dysfunction, because in these patients the left ventricular dysfunction in early hours after operation can reach the critical point leading to collapse of the circulation.Summary in EnglishAvailable from STL, Prague, CZ / NTK - National Technical LibrarySIGLECZCzech Republi