THE CHARACTERISTICS OF THE AMPEROMETRIC CHOLINESTERASE BIOSENSOR AS UNSTANDARD MEANS OF MEASURE

The inhibiting action of the number of the phosphor-, chlor- and nitrogenorganic pesticides has been investigated with the aid of the biochemical cholinesterase sensor. The kinetic parameters of the fermentative reaction in the presence of the organic inhibitors have been determined, the type of inhibiting has been established. The bank of data, allowing to evaluate the errors with the biosensor operation and to perform the metrolodical certification of the given unstandard means of measure, has been collected. The variant of the immunoferment sensor has been developed for the quantitative and qualitative evaluation of the content of the anthrax virus. The errors have been evaluated and the ways of its reduction in the work with biosensor have been planned. The methods of analysis with lower boundary of the contents to be determined on the MPC level and on several orders lower have been offered. The principal ways for the development of the new immunoferment sensors of the diagnostics of a wide circle of the compounds, entering the reactions of the biospecific interaction, have been planned. The recommendations on avoiding the number of errors in the work with biosensor as the non-standard means of measure, have been developedAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio