The work is aimed at creating the bank of genes B.pertussis, cloning of genes of the hooping-cough toxin and constructing the strain-producer of the hooping-cough toxin in the heterologous microorganism. For the first time, the presence of the hooping-cough toxin genes in the genomes of some microbes, kin Bordetell being in the unfunctional state has been shown. Cells B. bronchiseptica preserve the processing mechanisms, mechanisms of assembly and transport of the hooping-cough toxin to the outside medium. The series of plasmides bearing the hooping-cough toxin genes in its composition under control of the own as well as heterologous Lac-promotor, E.coli have been created. Constructed have been two strains-producers of the biologically acti...
We report the development of techniques for the genetic mapping of point mutations in the bacterial ...
The disease pertussis, more commonly known as whooping cough, is caused by the gram negative bacteri...
Pertussis toxin, a protein composed of five different subunits (S1, S2, S3, S4, and S5), is the majo...
Bordetella pertussis is the causative agent of whooping cough, a contagious childhood respiratory di...
Aim. The construction of recombinant attenuated Bordetella pertussis bacteria of ptxP3 genotype and ...
Pertussis is a highly contagious human respiratory illness caused by the bacterial pathogen Bordetel...
Bordetella pertussis, the etiologic agent of whooping cough or pertussis, produces a multitude of vi...
We have used pulsed-field gel electrophoresis to derive a restriction map of the chromosome of Borde...
The pathogenic microbe, Bordetella pertussis, is most recognizable for causing the disease commonly ...
Pertussis toxin (PT) is an essential component of accellular vaccines against whooping cough. Howeve...
The vir locus of Bordetella pertussis apparently encodes a trans-acting positive regulator that is r...
Includes bibliographical references (pages [42]-47)Initial investigations into the molecular biology...
In these studies, the Bordetella pertussis adenylate cyclase toxin-hemolysin homology to the Escheri...
Bordetella pertussis is the causative agent of whooping cough, a contagious childhood respiratory di...
Recently, a novel type of regulatory mutation causing differential effects on the expression of viru...
We report the development of techniques for the genetic mapping of point mutations in the bacterial ...
The disease pertussis, more commonly known as whooping cough, is caused by the gram negative bacteri...
Pertussis toxin, a protein composed of five different subunits (S1, S2, S3, S4, and S5), is the majo...
Bordetella pertussis is the causative agent of whooping cough, a contagious childhood respiratory di...
Aim. The construction of recombinant attenuated Bordetella pertussis bacteria of ptxP3 genotype and ...
Pertussis is a highly contagious human respiratory illness caused by the bacterial pathogen Bordetel...
Bordetella pertussis, the etiologic agent of whooping cough or pertussis, produces a multitude of vi...
We have used pulsed-field gel electrophoresis to derive a restriction map of the chromosome of Borde...
The pathogenic microbe, Bordetella pertussis, is most recognizable for causing the disease commonly ...
Pertussis toxin (PT) is an essential component of accellular vaccines against whooping cough. Howeve...
The vir locus of Bordetella pertussis apparently encodes a trans-acting positive regulator that is r...
Includes bibliographical references (pages [42]-47)Initial investigations into the molecular biology...
In these studies, the Bordetella pertussis adenylate cyclase toxin-hemolysin homology to the Escheri...
Bordetella pertussis is the causative agent of whooping cough, a contagious childhood respiratory di...
Recently, a novel type of regulatory mutation causing differential effects on the expression of viru...
We report the development of techniques for the genetic mapping of point mutations in the bacterial ...
The disease pertussis, more commonly known as whooping cough, is caused by the gram negative bacteri...
Pertussis toxin, a protein composed of five different subunits (S1, S2, S3, S4, and S5), is the majo...