Drogendetektionsgeraet auf Basis von Biosensoren. Teilprojekt: Elektrochemisches Enzym-Immuno-Sensor-System. Phase 1 Abschlussbericht

High-sensitive biosensors for drug (especially cocaine) detection in the air have been developed. By recycling enzyme amplification using the enzyme systems lactate oxidase/lactate dehydrogenase and laccase/NADH-independent glucose dehydrogenase with amperometric detection, picomolar substrate determination could be achieved. The enzymes coimmobilised on polyurethane are stable over 14 days with an amplifier gain of 700. For practical drug detection a combination with a newly developed immuno reactor is proposed. (WEN)Available from TIB Hannover: F95B1291+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Forschung und Technologie (BMFT), Bonn (Germany)DEGerman