Untersuchungen zur Signalsequenzfunktion und zur Funktion SecE-homologer Proteine in Gram-positiven Bakterien

The SecE homologeous gen of Staphylococcus carnosus has been isolated and characterized. This protein exhibits perfect functional homology to the Escherichia coli SecE protein. The gram-negative signal sequence of the pre-ompa protein from E.coli is recognized in the (gram-positive) organism of B. subtilis and exhibits the same functional efficiency as the gram-positive preprolipase signal peptide. It is concluded that the mechanism of protein translocation in gram-positive and gram-negative bacteria are largely conserved. (WEN)SIGLEAvailable from TIB Hannover: RA 831(2874) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman