Add to ORKGIn order to help cancer researchers in understanding tumor heterogeneity and its evolutionary dynamics, we propose a software pipeline to explore intra-tumor heterogeneity by means of scDNA sequencing data
Tumor cells have heterogeneous genotypes, which drives progression and treatment resistance. Such ge...
Single cell genomics offers an unprecedented resolution to interrogate genetic heterogeneity in a pa...
Almost all biomedical research to date has relied upon mean measurements from cell populations, howe...
Nowadays, single-cell DNA (sc-DNA) sequencing is showing up to be a valuable instrument to investiga...
Cellular heterogeneity is a fundamental characteristic of many cancers. A lack of cellular homogenei...
The use of single-cell DNA sequencing (sc-seq) techniques for the diagnosis, prognosis and treatment...
It is well known that cancer is an aggressive disease, often associated with relapse, in many cases ...
Although all cells in a human body are descendant from a single cell –i.e. the zygote– the genetic c...
Genome-wide analysis at the level of single cells has recently emerged as a powerful tool to dissect...
Single-cell sequencing: Greater insight through integrated data Combining data from different single...
As sequencing efforts continue to reveal the extent of the intratumor heterogeneity (ITH) present in...
Abstract Cancers are a group of heterogeneous diseases characterized by the acquisition of functiona...
Abstract It has become increasingly clear that both normal and cancer tissues are composed of hetero...
Broadly speaking, this thesis combines two subjects: advances of single cell sequencing technolgies,...
Single-cell DNA sequencing (scDNA-seq) helps researchers study the evolutionary process of cancer. I...
Tumor cells have heterogeneous genotypes, which drives progression and treatment resistance. Such ge...
Single cell genomics offers an unprecedented resolution to interrogate genetic heterogeneity in a pa...
Almost all biomedical research to date has relied upon mean measurements from cell populations, howe...
Nowadays, single-cell DNA (sc-DNA) sequencing is showing up to be a valuable instrument to investiga...
Cellular heterogeneity is a fundamental characteristic of many cancers. A lack of cellular homogenei...
The use of single-cell DNA sequencing (sc-seq) techniques for the diagnosis, prognosis and treatment...
It is well known that cancer is an aggressive disease, often associated with relapse, in many cases ...
Although all cells in a human body are descendant from a single cell –i.e. the zygote– the genetic c...
Genome-wide analysis at the level of single cells has recently emerged as a powerful tool to dissect...
Single-cell sequencing: Greater insight through integrated data Combining data from different single...
As sequencing efforts continue to reveal the extent of the intratumor heterogeneity (ITH) present in...
Abstract Cancers are a group of heterogeneous diseases characterized by the acquisition of functiona...
Abstract It has become increasingly clear that both normal and cancer tissues are composed of hetero...
Broadly speaking, this thesis combines two subjects: advances of single cell sequencing technolgies,...
Single-cell DNA sequencing (scDNA-seq) helps researchers study the evolutionary process of cancer. I...
Tumor cells have heterogeneous genotypes, which drives progression and treatment resistance. Such ge...
Single cell genomics offers an unprecedented resolution to interrogate genetic heterogeneity in a pa...
Almost all biomedical research to date has relied upon mean measurements from cell populations, howe...