The vertebrate body axes anterio-posterior, dorso-ventral and left-right are determined during early embryogenesis. In all phases of axis development transcription factors of the homeobox family play a pivotal role. In this work two important homeobox genes in axis formation, goosecoid and Pitx2, were analyses. In the early 20"t"h century Hans Spemann and Hilde Mangold identified the upper dorsal blastopore lip as the amphibian organiser of gastrulation. Their classical experiments showed that the transplantation of organiser tissue into a host embryo induced the formation of a complete secondary axis. The homeobox gene goosecoid (gsc) is expressed in all vertebrate organisers and has an axis-inducing potential in misexpression ex...
The Xenopus homeobox gene Xhox3 shows a graded expression in the axial mesoderm, with the highest co...
The Hox genes are a class of putative developmental control genes that are thought to be involved in...
The homeobox gene goosecoid is one of the first genes expressed in the organizer region of vertebrat...
A fundamental question in developmental biology is to understand the mechanisms that govern the deve...
AbstractThe experimental manipulation of early embryologic events, resulting in the misexpression of...
The homeobox gene goosecoid, originally identified in Xenopus, is expressed in the organizer or its ...
The internal organs of all vertebrates are asymmetrically organised across the left-right axis. The ...
AbstractThe mechanism by which asymmetric signals induce left-right-specific morphogenesis has been ...
AbstractNodal and Nodal-related factors play fundamental roles in a number of developmental processe...
Abstract Background Left-right (LR) asymmetry is an essential feature of bilateral animals. Studies ...
AbstractPitx2, a member of the bicoid-related family of homeobox-containing genes, is asymmetrically...
AbstractThe homeobox gene goosecoid was the first specific genetic marker of Spemann's organizer in ...
Hox genes are a very important family of transcription factors during development of vertebrate and ...
The formation and anteroposterior patterning of the three definitive germ layers, ectoderm, mesoderm...
The molecular nature of Spemann's organizer phenom-enon has long attracted the attention of emb...
The Xenopus homeobox gene Xhox3 shows a graded expression in the axial mesoderm, with the highest co...
The Hox genes are a class of putative developmental control genes that are thought to be involved in...
The homeobox gene goosecoid is one of the first genes expressed in the organizer region of vertebrat...
A fundamental question in developmental biology is to understand the mechanisms that govern the deve...
AbstractThe experimental manipulation of early embryologic events, resulting in the misexpression of...
The homeobox gene goosecoid, originally identified in Xenopus, is expressed in the organizer or its ...
The internal organs of all vertebrates are asymmetrically organised across the left-right axis. The ...
AbstractThe mechanism by which asymmetric signals induce left-right-specific morphogenesis has been ...
AbstractNodal and Nodal-related factors play fundamental roles in a number of developmental processe...
Abstract Background Left-right (LR) asymmetry is an essential feature of bilateral animals. Studies ...
AbstractPitx2, a member of the bicoid-related family of homeobox-containing genes, is asymmetrically...
AbstractThe homeobox gene goosecoid was the first specific genetic marker of Spemann's organizer in ...
Hox genes are a very important family of transcription factors during development of vertebrate and ...
The formation and anteroposterior patterning of the three definitive germ layers, ectoderm, mesoderm...
The molecular nature of Spemann's organizer phenom-enon has long attracted the attention of emb...
The Xenopus homeobox gene Xhox3 shows a graded expression in the axial mesoderm, with the highest co...
The Hox genes are a class of putative developmental control genes that are thought to be involved in...
The homeobox gene goosecoid is one of the first genes expressed in the organizer region of vertebrat...