Bildrekonstruktion und Bildrestauration fuer die optische Streulichttomographie Abschlussbericht

The aim of this research project was the development of efficient image reconstruction algorithms for a computed tomography with scattered light. With the transillumination of a tissue volume from different light source positions it is possible to obtain an integral information about the internal optical structure (absorption and scattering coefficients) of the volume. The application of mathematical reconstruction algorithms is then useful to recompute the spatial parameter distribution in the probe volume. In the course of our work a number of program systems for modelling the light propagation in scattering media have been developed. On the basis of these forward models two efficient image reconstruction algorithms were implemented which take the physical nature of diffuse photon propagation into account. As a main result we have developed a real-time reconstruction algorithm that is suitable for monitoring systems. All reconstruction algorithms were verified by real measurement data from phantoms as well as from biological objects (rat brain). Further investigations were carried out on the problems of image restauration for optical screening and the quantitation of optical parameters from scattered light measurement data. (orig.)SIGLEAvailable from TIB Hannover: F98B908+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman