In vitro approaches to the prediction of percutaneous absorption and metabolism A study of ethoxylates

The use of in vitro metabolism techniques in the planning and interpretation of drug safety studies

Steven A. Wrighton
Barbara J. Ring
Mark Vandenbranden

January 1995

An important issue in toxicology is the suitability of the data obtained with experimental animals f...

Predicting the Extent of Metabolism Using in Vitro Permeability Rate Measurements and in Silico Permeability Rate Predictions

Chelsea M. Hosey (1607545)
Leslie Z. Benet (1314297)

May 2015

The Biopharmaceutics Drug Disposition Classification System (BDDCS) can be utilized to predict drug ...

In situ perfusion in rodents to explore intestinal drug absorption: Challenges and opportunities

Stappaerts, Jef
Brouwers, Joachim
Annaert, Pieter
Augustijns, Patrick

January 2015

The in situ intestinal perfusion technique in rodents is a very important absorption model, not only...

In vitro percutaneous absorption of agrochemicals Kinetic and metabolic studies

Hewitt, P.G

January 1996

SIGLEAvailable from British Library Document Supply Centre-DSC:DXN006583 / BLDSC - British Library D...

In vitro models for the prediction of dermal absorption of chemicals

Dick, I.P.
Williams, F.M.
Health and Safety Executive, London (United Kingdom)

January 1998

SIGLEAvailable from British Library Document Supply Centre-DSC:4335.321(178/1998) / BLDSC - British ...

Investigating the modulation of oral drug absorption using in vitro models

Biggs, Jonathan Robert

January 2003

SIGLEAvailable from British Library Document Supply Centre- DSC:DXN064631 / BLDSC - British Library ...

Percutaneous Absorption. On the Relevance of in Vitro Data

Franz, Thomas J

March 1975

The use of in vitro preparations of human skin to study percutaneous absorption is widespread. Yet, ...

In Vitro Metabolism and Bioavailability Test for Endocrine Active Substances: What is Needed Next for Regulatory Purposes?

Jacobs, M.N.
Laws, S.C.
Willett, K.
Schmieder, P.
Odum, B.
Bovee, T.F.H.

January 2013

Legislation and prospective legislative proposals internationally (may) require that chemicals be te...

Biotransformation in vitro: an essential consideration in the quantitative in vitro-to-in vivo extrapolation (QIVIVE) of toxicity data

WILK-ZASADNA IWONA
BERNASCONI CAMILLA
PELKONEN OLAVI
COECKE SANDRA

January 2014

Early consideration of the multiplicity of factors that govern the biological fate of foreign compou...

The use of in vitro models for mechanistic studies in toxicology

Westmoreland, C.

January 1997

SIGLEAvailable from British Library Document Supply Centre-DSC:DXN014281 / BLDSC - British Library D...

Cutaneous xenobiotic metabolism and its role in percutaneous absorption

Clark, N.W.E

January 1992

SIGLEAvailable from British Library Document Supply Centre- DSC:DX174600 / BLDSC - British Library D...

Strategies for absorption screening in drug discovery and development

Bohets, H
Annaert, Pieter
Mannens, G
Van Beijsterveldt, L
Anciaux, K
Verboven, P
Meuldermans, W
Lavrijsen, K

November 2001

This review gives an overview of the current approaches to evaluate drug absorption potential in the...

The use of human in vitro metabolic parameters to explore the risk assessment of hazardous compounds: The case of ethylene dibromide.

Ploemen, J.P.H.T.M.
Wormhoudt, L.W.
Haenen, G.R.M.M.
Oudshoorn, M.J.
Commandeur, J.N.M.
Vermeulen, N.P.E.
De Waziers, I.
Beaune, P.H.
Watabe, T.
van Bladeren, P.J.

January 1997

Ethylene dibromide (1,2-dibromoethane, EDB) is metabolized by two routes: a conjugative route cataly...

In Vitro-in Vivo Correlation of Percutaneous Absorption : Isosorbide Dinitrate and Morphine Hydrochloride

畑中, 朋美
片山, 和憲
小泉, 保
杉林, 賢次
森本, 雍憲

June 1994

The potential of an in vitro skin preparation as a model for predicting in vivo percutaneous absorpt...

Methodology for the assessment of lipid peroxidation in vivo and in vitro

Briggs, R.J

January 1994

SIGLEAvailable from British Library Document Supply Centre- DSC:DX185186 / BLDSC - British Library D...

The use of in vitro metabolism techniques in the planning and interpretation of drug safety studies

Steven A. Wrighton
Barbara J. Ring
Mark Vandenbranden

January 1995

An important issue in toxicology is the suitability of the data obtained with experimental animals f...

Predicting the Extent of Metabolism Using in Vitro Permeability Rate Measurements and in Silico Permeability Rate Predictions

Chelsea M. Hosey (1607545)
Leslie Z. Benet (1314297)

May 2015

The Biopharmaceutics Drug Disposition Classification System (BDDCS) can be utilized to predict drug ...

In situ perfusion in rodents to explore intestinal drug absorption: Challenges and opportunities

Stappaerts, Jef
Brouwers, Joachim
Annaert, Pieter
Augustijns, Patrick

January 2015

The in situ intestinal perfusion technique in rodents is a very important absorption model, not only...

In vitro percutaneous absorption of agrochemicals Kinetic and metabolic studies

Hewitt, P.G

January 1996

SIGLEAvailable from British Library Document Supply Centre-DSC:DXN006583 / BLDSC - British Library D...

In vitro models for the prediction of dermal absorption of chemicals

Dick, I.P.
Williams, F.M.
Health and Safety Executive, London (United Kingdom)

January 1998

SIGLEAvailable from British Library Document Supply Centre-DSC:4335.321(178/1998) / BLDSC - British ...

Investigating the modulation of oral drug absorption using in vitro models

Biggs, Jonathan Robert

January 2003

SIGLEAvailable from British Library Document Supply Centre- DSC:DXN064631 / BLDSC - British Library ...

Percutaneous Absorption. On the Relevance of in Vitro Data

Franz, Thomas J

March 1975

The use of in vitro preparations of human skin to study percutaneous absorption is widespread. Yet, ...

In Vitro Metabolism and Bioavailability Test for Endocrine Active Substances: What is Needed Next for Regulatory Purposes?

Jacobs, M.N.
Laws, S.C.
Willett, K.
Schmieder, P.
Odum, B.
Bovee, T.F.H.

January 2013

Legislation and prospective legislative proposals internationally (may) require that chemicals be te...

Biotransformation in vitro: an essential consideration in the quantitative in vitro-to-in vivo extrapolation (QIVIVE) of toxicity data

WILK-ZASADNA IWONA
BERNASCONI CAMILLA
PELKONEN OLAVI
COECKE SANDRA

January 2014

Early consideration of the multiplicity of factors that govern the biological fate of foreign compou...

The use of in vitro models for mechanistic studies in toxicology

Westmoreland, C.

January 1997

SIGLEAvailable from British Library Document Supply Centre-DSC:DXN014281 / BLDSC - British Library D...

Cutaneous xenobiotic metabolism and its role in percutaneous absorption

Clark, N.W.E

January 1992

SIGLEAvailable from British Library Document Supply Centre- DSC:DX174600 / BLDSC - British Library D...

Strategies for absorption screening in drug discovery and development

Bohets, H
Annaert, Pieter
Mannens, G
Van Beijsterveldt, L
Anciaux, K
Verboven, P
Meuldermans, W
Lavrijsen, K

November 2001

This review gives an overview of the current approaches to evaluate drug absorption potential in the...

The use of human in vitro metabolic parameters to explore the risk assessment of hazardous compounds: The case of ethylene dibromide.

Ploemen, J.P.H.T.M.
Wormhoudt, L.W.
Haenen, G.R.M.M.
Oudshoorn, M.J.
Commandeur, J.N.M.
Vermeulen, N.P.E.
De Waziers, I.
Beaune, P.H.
Watabe, T.
van Bladeren, P.J.

January 1997

Ethylene dibromide (1,2-dibromoethane, EDB) is metabolized by two routes: a conjugative route cataly...

In Vitro-in Vivo Correlation of Percutaneous Absorption : Isosorbide Dinitrate and Morphine Hydrochloride

畑中, 朋美
片山, 和憲
小泉, 保
杉林, 賢次
森本, 雍憲

June 1994

The potential of an in vitro skin preparation as a model for predicting in vivo percutaneous absorpt...

Methodology for the assessment of lipid peroxidation in vivo and in vitro

Briggs, R.J

January 1994

SIGLEAvailable from British Library Document Supply Centre- DSC:DX185186 / BLDSC - British Library D...

The use of in vitro metabolism techniques in the planning and interpretation of drug safety studies

Steven A. Wrighton
Barbara J. Ring
Mark Vandenbranden

January 1995

An important issue in toxicology is the suitability of the data obtained with experimental animals f...

Predicting the Extent of Metabolism Using in Vitro Permeability Rate Measurements and in Silico Permeability Rate Predictions

Chelsea M. Hosey (1607545)
Leslie Z. Benet (1314297)

May 2015

The Biopharmaceutics Drug Disposition Classification System (BDDCS) can be utilized to predict drug ...

In situ perfusion in rodents to explore intestinal drug absorption: Challenges and opportunities

Stappaerts, Jef
Brouwers, Joachim
Annaert, Pieter
Augustijns, Patrick

January 2015

The in situ intestinal perfusion technique in rodents is a very important absorption model, not only...

In vitro approaches to the prediction of percutaneous absorption and metabolism A study of ethoxylates

Abstract

Extracted data

In vitro approaches to the prediction of percutaneous absorption and metabolism A study of ethoxylates

Abstract

Extracted data

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