Continuum d'organisation structurale de la solution à l'hydrogel physique de polysaccharides

The study of the morphology of natural polysaccharide solutions of controlled molecular structure is considered as the core of the development of materials decoy of biological media , based on physical hydrogels. First, we present a controlled method to obtain polysaccharides of precise molecular weights and low polydispersity or a collection of oligomers. Second, the multi-scale organization of polysaccharide polyelectrolytes in solution was investigated and we proposed a method to evaluate the balance between hydrophilic and hydrophobic interactions governing the behaviour of these systems. The structural relationship between the solution and the hydrogel is illustrated in the case of chitosan, a model decoy polyelectrolyte. Finally, new directions for the elaboration of chitosan based multifunctional hydrogel materials are discussedLYON1-BU.Sciences (692662101) / SudocSudocFranceF