Double strand break repair and DNA damage signalling pathways in Arabidopsis

The external environment and internal cellular processes generate DNA double strand breaks (DSBs), a particularly toxic form of DNA damage that can result in chromosome fragmentation, replication failure, mutagenesis and cell death. Cells have evolved effective mechanisms to preserve the mtegrity of the genome including DNA damage signalling, cell cycle checkpoint activation and DNA repair.EThOS - Electronic Theses Online ServiceGBUnited Kingdo