Function of the bacterial cytoskeleton in the biology and pathogenicity of salmonella

The bacterial cytoskeleton contains structural and functional homologues of actin, tubulin and intermediate filament-like proteins. In Escherichia.coli (E.coli) and Bacillus.subtilis (B.subtilis), the bacterial actin homologue mreB, along with mreC and mreD are all involved in cell shape determination. In silico searches confirmed the presence of actin gene J |: homologues in Salmonella. The putative cytoskeletal genes of Salmonella Typhimurium mreB, mreC, and mreD, he in close proximity to four additional genes named; maf, cafA, yhdP, and tldD. Evidence was provided which to suggest they are part of the mreB operon.EThOS - Electronic Theses Online ServiceGBUnited Kingdo