Add to ORKGIntegration of gamma-retroviruses (RV) and lehtiviruses (LV) follows different, non random patterns in mammalian genomes. To obtain information about the viral and genomic determinants of integration preferences, I mapped > 2,500 integration sites of RV and LV vectors carrying wild type or modified LTRs in human CD34+ hematopoietic cells. To investigate the role of transcriptional regulatory networks in directing RV and LV integration, 1 evaluated the local abundance and anangement of putative transcription factor binding sites (TFBSs) in the genomic regions flanking integrated proviruses.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
Retroviral integration is a non-random process, whereby pre-integration complexes of different virus...
An essential step of the life cycle of retroviruses is the stable insertion of a copy of their DNA g...
Integration of retroviral vectors in the human genome follows non random patterns that favor inserti...
Gamma-retroviruses and lentiviruses integrate non-randomly in mammalian genomes, with specific prefe...
Integration of gamma-retroviruses (RV) and lentiviruses (LV) follows different, non-random patterns ...
<div><p>The completion of the human genome sequence has made possible genome-wide studies of retrovi...
The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA ...
The stable insertion of a copy of their genome into the host cell genome is an essential step of the...
Upon cell invasion, retroviruses integrate the retroviral cDNA within the host chromosomal DNA. Inte...
Retroviral replication proceeds through an obligate integrated DNA provirus, making retroviral vecto...
Upon cell invasion, retroviruses generate a DNA copy of their RNA genome and integrate retroviral cD...
Integration of retroviral cDNA into the host cell genome is a process central to the replication cyc...
Integration of retroviral vectors in the human genome follows nonrandom patterns that favor insertio...
Insertional oncogenesis is a possible consequence of the integration of gamma-retroviral (RV) or len...
Abstract Background The randomness of retroviral integration has been debated for many years. Recent...
Retroviral integration is a non-random process, whereby pre-integration complexes of different virus...
An essential step of the life cycle of retroviruses is the stable insertion of a copy of their DNA g...
Integration of retroviral vectors in the human genome follows non random patterns that favor inserti...
Gamma-retroviruses and lentiviruses integrate non-randomly in mammalian genomes, with specific prefe...
Integration of gamma-retroviruses (RV) and lentiviruses (LV) follows different, non-random patterns ...
<div><p>The completion of the human genome sequence has made possible genome-wide studies of retrovi...
The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA ...
The stable insertion of a copy of their genome into the host cell genome is an essential step of the...
Upon cell invasion, retroviruses integrate the retroviral cDNA within the host chromosomal DNA. Inte...
Retroviral replication proceeds through an obligate integrated DNA provirus, making retroviral vecto...
Upon cell invasion, retroviruses generate a DNA copy of their RNA genome and integrate retroviral cD...
Integration of retroviral cDNA into the host cell genome is a process central to the replication cyc...
Integration of retroviral vectors in the human genome follows nonrandom patterns that favor insertio...
Insertional oncogenesis is a possible consequence of the integration of gamma-retroviral (RV) or len...
Abstract Background The randomness of retroviral integration has been debated for many years. Recent...
Retroviral integration is a non-random process, whereby pre-integration complexes of different virus...
An essential step of the life cycle of retroviruses is the stable insertion of a copy of their DNA g...
Integration of retroviral vectors in the human genome follows non random patterns that favor inserti...