Type-1 diabetes is caused by autoimmune destruction of insulin-producing β-cells in the pancreas. Today, transplantation of whole pancreas or islets is the only treatment that can restore endogenous insulin production. Within the past 20 years, pancreatic islet transplantation has become a clinical reality and an option in diabetes treatment. However, large use of this therapy is limited by shortage in organ donations and use of immunosuppressive drugs. Immunoisolation potentially allows elimination of immuosuppressive drugs and use of xenogenic tissue solving the problem of a shortage in organ donation.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
Shapiro and colleagues recently reported a 100% cure rate for type 1 diabetes with their “Edmonton p...
Type 1 diabetes mellitus (T1DM) is associated with chronic complications that lead to high morbidity...
Type 1 diabetes mellitus (T1DM) is associated with chronic complications that lead to high morbidity...
Type 1 diabetes is a disease resulting from autoimmune destruction of the insulin-producing beta cel...
The discovery of insulin changed the course of history in the treatment of diabetes. However, despit...
Currently, for the patient with type 1 diabetes, a definitive treatment without resorting to the use...
Abstract Background No formulation of exogenous insulin available to date has yet been able to m...
Successful pancreas or islet transplantation is currently the only cure for type 1 diabetes mellitus...
The main goal of treatment for type 1 diabetes is to control glycaemia with insulin therapy to reduc...
Pancreatic islet cell transplantation as a treatment modality for type 1 diabetes mellitus (T1 DM) h...
The ability to achieve insulin independence with either solid-organ pancreas or islet transplantatio...
Islet cell transplantation is categorized as a β-cell replacement therapy for diabetic patients who ...
The main goal of treatment for type 1 diabetes is to control glycaemia with insulin therapy to reduc...
Summary: The only known cure for insulin-dependent diabetes mellitus is transplantation of functioni...
Islet cell transplantation recently has emerged as one the most promising therapeutic approaches to ...
Shapiro and colleagues recently reported a 100% cure rate for type 1 diabetes with their “Edmonton p...
Type 1 diabetes mellitus (T1DM) is associated with chronic complications that lead to high morbidity...
Type 1 diabetes mellitus (T1DM) is associated with chronic complications that lead to high morbidity...
Type 1 diabetes is a disease resulting from autoimmune destruction of the insulin-producing beta cel...
The discovery of insulin changed the course of history in the treatment of diabetes. However, despit...
Currently, for the patient with type 1 diabetes, a definitive treatment without resorting to the use...
Abstract Background No formulation of exogenous insulin available to date has yet been able to m...
Successful pancreas or islet transplantation is currently the only cure for type 1 diabetes mellitus...
The main goal of treatment for type 1 diabetes is to control glycaemia with insulin therapy to reduc...
Pancreatic islet cell transplantation as a treatment modality for type 1 diabetes mellitus (T1 DM) h...
The ability to achieve insulin independence with either solid-organ pancreas or islet transplantatio...
Islet cell transplantation is categorized as a β-cell replacement therapy for diabetic patients who ...
The main goal of treatment for type 1 diabetes is to control glycaemia with insulin therapy to reduc...
Summary: The only known cure for insulin-dependent diabetes mellitus is transplantation of functioni...
Islet cell transplantation recently has emerged as one the most promising therapeutic approaches to ...
Shapiro and colleagues recently reported a 100% cure rate for type 1 diabetes with their “Edmonton p...
Type 1 diabetes mellitus (T1DM) is associated with chronic complications that lead to high morbidity...
Type 1 diabetes mellitus (T1DM) is associated with chronic complications that lead to high morbidity...