Efficacy and safety of paediatric immunization-linked intermittent preventive treatment in infants (IPTi) in the prevention of malaria morbidity in rural western Kenya

Background: Intermittent preventive treatment in infants (IPTi) with sulphadoxine-pyrimethamine (SP) for the prevention of malaria has shown encouraging results in recent trials. However, resistance to SP is rising and alternative drugs for IPTi need to be evaluated. Objectives: To evaluate the safety and efficacy of different drugs for IPTi and to better understand the role of treatment vs. prophylactic effect of IPTi by comparing short and long-acting antimalarials.EThOS - Electronic Theses Online ServiceGBUnited Kingdo