Management of severe acute pancreatitis

The clinical management of severe acute pancreatitis has improved significantly in the last decade, mainly due to advances in supportive critical care. However, it still poses formidable problems to the clinician, due to lack of uniformity in early disease definition, absence of disease specific treatment and paucity of evidence base for management of complications. This thesis attempts to address these problems using inter-related studies based on clinical (cohort study and randomised control trial), experimental and data-analysis methodologies.EThOS - Electronic Theses Online ServiceGBUnited Kingdo