Add to ORKGIn an effort to find antimalarial drugs, a systematic in vitro evaluation on a chloroquine-resistant strain of Plasmodium falciparum (FcB1) was undertaken on sixty plant extracts collected in French Guiana. The ethyl acetate extract obtained from the root barks of Symphonia globulifera exhibited a strong antiplasmodial activity (97% at 10 mu g/ml). The phytochemical investigation of this extract led to the isolation of nine polycyclic polyprenylated acylphloroglucinol (PPAPs) compounds and two oxidized derivatives. All compounds showed antiplasmodial activity with IC(50)s ranged from 2.1 to 10.1 mu M. A LC/ESI-MSn study performed on polyprenylated benzophenones previously isolated from Moronobea coccinea provided a reliable method for their...
Nguengang RT, Tchegnitegni BT, Nono ECN, et al. Constituents of the Stem Bark of Symphonia globulife...
Morus mesozygia Stapf (Moraceae) is a plant found in many regions and used in treating many diseases...
Un criblage biologique sur l activité antiplasmodiale de plantes de la famille des Clusiaceae et des...
In an effort to find antimalarial drugs, a systematic in vitro evaluation on a chloroquine-resistant...
There is continuing need for new and improved drugs to tackle malaria, which remains a major public ...
Malaria is one of the world's leading killer infectious diseases, with an estimated 300-500 million ...
A total of 33 extracts of eleven different plants species from Mata Atl?ntica biome, Brazil, and dif...
Plasmodium is a blood protozoan parasite that is responsible for malaria. To date, Plasmodium falcip...
International audienceImproved methodological tools to hasten antimalarial drug discovery remain of ...
Malaria, as a major global health problem, continues to affect a large number of people each year, e...
Malaria is known as the most important parasitic disease around the world with 584 000 malaria death...
C. pareira L. is a centuries-old traditional medicinal plant utilized to treat various diseases like...
Ethnopharmacological Relevance. Development of resistance to antimalarial drugs by Plasmodium falcip...
In the search of active principles from the stem bark of Entandrophragma angolense , we submitted t...
Search for natural products that can be developed into drugs for treatment of tropical diseases su...
Nguengang RT, Tchegnitegni BT, Nono ECN, et al. Constituents of the Stem Bark of Symphonia globulife...
Morus mesozygia Stapf (Moraceae) is a plant found in many regions and used in treating many diseases...
Un criblage biologique sur l activité antiplasmodiale de plantes de la famille des Clusiaceae et des...
In an effort to find antimalarial drugs, a systematic in vitro evaluation on a chloroquine-resistant...
There is continuing need for new and improved drugs to tackle malaria, which remains a major public ...
Malaria is one of the world's leading killer infectious diseases, with an estimated 300-500 million ...
A total of 33 extracts of eleven different plants species from Mata Atl?ntica biome, Brazil, and dif...
Plasmodium is a blood protozoan parasite that is responsible for malaria. To date, Plasmodium falcip...
International audienceImproved methodological tools to hasten antimalarial drug discovery remain of ...
Malaria, as a major global health problem, continues to affect a large number of people each year, e...
Malaria is known as the most important parasitic disease around the world with 584 000 malaria death...
C. pareira L. is a centuries-old traditional medicinal plant utilized to treat various diseases like...
Ethnopharmacological Relevance. Development of resistance to antimalarial drugs by Plasmodium falcip...
In the search of active principles from the stem bark of Entandrophragma angolense , we submitted t...
Search for natural products that can be developed into drugs for treatment of tropical diseases su...
Nguengang RT, Tchegnitegni BT, Nono ECN, et al. Constituents of the Stem Bark of Symphonia globulife...
Morus mesozygia Stapf (Moraceae) is a plant found in many regions and used in treating many diseases...
Un criblage biologique sur l activité antiplasmodiale de plantes de la famille des Clusiaceae et des...