Add to ORKGAlthough the genus Enterovirus contains many important human pathogens, there is no licensed drug for either the treatment or the prophylaxis of enterovirus infections. We report that fluoxetine (Prozac)—a selective serotonin reuptake inhibitor—inhibits the replication of human enterovirus B (HEV-B) and HEV-D but does not affect the replication of HEV-A and HEV-C or human rhinovirus A or B. We show that fluoxetine interferes with viral RNA replication, and we identified viral protein 2C as the target of this compound
Enteroviruses (EVs) represent many important pathogens of humans. Unfortunately, no antiviral compou...
The enterovirus genus encompasses many clinically important human pathogens such as poliovirus, coxs...
To circumvent time-consuming clinical trials, testing whether existing drugs are effective inhibitor...
Although the genus Enterovirus contains many important human pathogens, there is no licensed drug fo...
Although the genus Enterovirus contains many important human pathogens, there is no licensed drug fo...
International audienceEnteroviruses (family Picornaviridae) comprise a large group of human pathogen...
Enteroviruses (family Picornaviridae) comprise a large group of human pathogens against which no lic...
Enteroviruses (EV) are a group of positive-strand RNA (+RNA) viruses that include many important hum...
This study reports the antiviral activity of the drug fluoxetine against some enteroviruses (EV). We...
Enteroviruses (EV) represent many important pathogens of humans. Unfortunately, no antiviral compoun...
Enteroviruses (EVs) represent many important pathogens of humans. Unfortunately, no antiviral compou...
The enterovirus genus encompasses many clinically important human pathogens such as poliovirus, coxs...
To circumvent time-consuming clinical trials, testing whether existing drugs are effective inhibitor...
Although the genus Enterovirus contains many important human pathogens, there is no licensed drug fo...
Although the genus Enterovirus contains many important human pathogens, there is no licensed drug fo...
International audienceEnteroviruses (family Picornaviridae) comprise a large group of human pathogen...
Enteroviruses (family Picornaviridae) comprise a large group of human pathogens against which no lic...
Enteroviruses (EV) are a group of positive-strand RNA (+RNA) viruses that include many important hum...
This study reports the antiviral activity of the drug fluoxetine against some enteroviruses (EV). We...
Enteroviruses (EV) represent many important pathogens of humans. Unfortunately, no antiviral compoun...
Enteroviruses (EVs) represent many important pathogens of humans. Unfortunately, no antiviral compou...
The enterovirus genus encompasses many clinically important human pathogens such as poliovirus, coxs...
To circumvent time-consuming clinical trials, testing whether existing drugs are effective inhibitor...