International audienceRieske dioxygenases are metalloenzymes capable of achieving cis-dihydroxylation of aromatics under mild conditions using O2 and a source of electrons. The intermediate responsible for this reactivity is proposed to be a cis-Fe V (O)(OH) moiety. Molecular models allow generating Fe III (OOH) species with H2O2, to yield a Fe V (O)(OH) species with tetradentate ligands, or {Fe IV (O)/OH•} pairs with pentadentate ones. We have designed a new pentadentate ligand mtL4 2 bearing a labile triazole, to generate an "in-between" situation. Two iron complexes [(mtL4 2)FeCl](PF6) and [(mtL4 2)Fe(OTf)2]) were obtained and their reactivity studied towards aromatic substrates in the presence of H2O2. Spectroscopic and kinetic studies ...
High-valent iron-oxo species have been invoked as reactive intermediates in catalytic cycles of heme...
The reactivity of [Fe-III(tpena)](2+) (tpena=N,N,N'-tris(2-pyridylmethyl)ethylenediamine-N-acetate) ...
A new class of functional models for non-heme iron-based dioxygenases, including [(N3Py-Me)Fe(CH3CN)...
Dioxygen activating nonheme iron enzymes are an important class of enzymes that are responsible for ...
There is a growing interest in probing the mechanism of catalytic transformations effected by non-he...
A detailed mechanistic study of the hydroxylation of alkane CH bonds using H2O2 by a family of monon...
ortho-Hydroxylation of aromatic compounds by non-heme Fe complexes has been extensively studied in r...
A new class of functional models for non-heme iron-based dioxygenases, including [(N3Py-Me)Fe(CH3CN)...
A new class of functional models for non-heme iron-based dioxygenases, including [(N3Py-Me)Fe(CH3CN)...
Recognizing Nature's unique ability to perform challenging oxygenation reactions with exquisite sele...
Ce travail s inscrit dans le cadre de la modélisation fonctionnelle de monooxygénases à fer capables...
A new class of functional models for non-heme iron-based dioxygenases, including [(N3Py-Me)Fe(CH3 CN...
The development of oxygen-tolerant H-2-evolving catalysts plays a vital role for a future H-2 econom...
The activation of dioxygen plays an important role in processes ranging from biological oxidation to...
Thesis (Ph. D.)--University of Rochester. Dept. of Chemistry, 2010.Extradiol catechol dioxygenases (...
High-valent iron-oxo species have been invoked as reactive intermediates in catalytic cycles of heme...
The reactivity of [Fe-III(tpena)](2+) (tpena=N,N,N'-tris(2-pyridylmethyl)ethylenediamine-N-acetate) ...
A new class of functional models for non-heme iron-based dioxygenases, including [(N3Py-Me)Fe(CH3CN)...
Dioxygen activating nonheme iron enzymes are an important class of enzymes that are responsible for ...
There is a growing interest in probing the mechanism of catalytic transformations effected by non-he...
A detailed mechanistic study of the hydroxylation of alkane CH bonds using H2O2 by a family of monon...
ortho-Hydroxylation of aromatic compounds by non-heme Fe complexes has been extensively studied in r...
A new class of functional models for non-heme iron-based dioxygenases, including [(N3Py-Me)Fe(CH3CN)...
A new class of functional models for non-heme iron-based dioxygenases, including [(N3Py-Me)Fe(CH3CN)...
Recognizing Nature's unique ability to perform challenging oxygenation reactions with exquisite sele...
Ce travail s inscrit dans le cadre de la modélisation fonctionnelle de monooxygénases à fer capables...
A new class of functional models for non-heme iron-based dioxygenases, including [(N3Py-Me)Fe(CH3 CN...
The development of oxygen-tolerant H-2-evolving catalysts plays a vital role for a future H-2 econom...
The activation of dioxygen plays an important role in processes ranging from biological oxidation to...
Thesis (Ph. D.)--University of Rochester. Dept. of Chemistry, 2010.Extradiol catechol dioxygenases (...
High-valent iron-oxo species have been invoked as reactive intermediates in catalytic cycles of heme...
The reactivity of [Fe-III(tpena)](2+) (tpena=N,N,N'-tris(2-pyridylmethyl)ethylenediamine-N-acetate) ...
A new class of functional models for non-heme iron-based dioxygenases, including [(N3Py-Me)Fe(CH3CN)...