International audienceLarge fluvial systems, such as the Nile River, allow a basin-scale integrated view of climatological and environmental changes. In this study, we reconstructed the Nile discharge history for the last 20 ka using molecular ratios of glycerol dialkyl glycerol tetraethers (GDGTs) and neodymium (Nd) radiogenic isotopes. By characterizing both the organic and inorganic fractions, we assessed the relevance of the GDGT-based proxies in deltaic environments as tracers of terrigenous origin. A large increase in Nile discharge is documented from 14.8 to 8.4 ka BP reflecting enhanced physical erosion and transport processes from the Ethiopian Traps. We confirmed the primary control of insolation on precipitation on North East Afr...