Generation of integration-free induced pluripotent stem cells from healthy individuals
- Yde Ohki, Cristine Marie
- Grossmann, Leoni
- Döring, Christian
- Hoffmann, Per
- Herms, Stefan
- Werling, Anna Maria
- Walitza, Susanne
- Grünblatt, Edna
DOIAbstract
Ten human induced pluripotent stem cell (iPSC) lines have been derived from five healthy controls matched to a study including Attention-Deficit Hyperactivity Disorder patients (ADHD). Both female and male children and adolescents aged 6-18 years were recruited. Isolated keratinocyte cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and cMyc
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