This thesis deals with the capture, annotation, synthesis and evaluation of arm and hand motions for the animation of avatars communicating in Sign Languages (SL). Currently, the production and dissemination of SL messages often depend on video recordings which lack depth information and for which editing and analysis are complex issues. Signing avatars constitute a powerful alternative to video. They are generally animated using either procedural or data-driven techniques. Procedural animation often results in robotic and unrealistic motions, but any sign can be precisely produced. With data-driven animation, the avatar's motions are realistic but the variety of the signs that can be synthesized is limited and/or biased by the initial data...