Apathy is not associated with reduced ventral striatal volume in patients with schizophrenia
- Burrer, Achim
- Caravaggio, Fernando
- Manoliu, Andrei
- Plitman, Eric
- Gütter, Karoline
- Habermeyer, Benedikt
- Stämpfli, Philipp
- Abivardi, Aslan
- Schmidt, André
- Borgwardt, Stefan
- Chakravarty, Mallar
- Lepage, Martin
- Dagher, Alain
- Graff-Guerrero, Ariel
- Seifritz, Erich
- Kaiser, Stefan
- Kirschner, Matthias
DOIAbstract
A growing body of neuroimaging research has revealed a relationship between blunted activation of the ventral striatum (VS) and apathy in schizophrenia. In contrast, the association between reduced striatal volume and apathy is less well established, while the relationship between VS function and structure in patients with schizophrenia remains an open question. Here, we aimed to replicate previous structural findings in a larger independent sample and to investigate the relationship between VS hypoactivation and VS volume
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