Italy’s regional inequalities are more substantial and persistent than any other European country. They pertain to fundamental economic indicators (income, productivity, employment) and to many relevant features of the socio-institutional environment (the quality of institutions, education attainments, government and bureaucratic efficiency, etc.). The 2008–13 crisis further exacerbated divergences, with a collapse of capital accumulation and unwelcome demographic shocks (brain drains, migrations, etc.). This paper contributes to this rich literature with a specific focus on the increase of ‘within-south inequalities’ and investigates some socioeconomic determinants and processes that can explain them. Through several original surveys and c...