Neurons are added throughout life in the hippocampus and olfactory bulb in most mammals, although humans represent an exception without detectable olfactory bulb neurogenesis. Nevertheless, neuroblasts are generated in the lateral ventricle wall in humans, the neurogenic niche for olfactory bulb neurons in other mammals. We show that, in humans, new neurons integrate adjacent to this neurogenic niche, in the striatum. The neuronal turnover in the striatum appears restricted to interneurons and we show that postnatally generated striatal neurons are preferentially depleted in Huntington’s disease. This demonstrates a unique pattern of neurogenesis in the adult human brain. Linnéprojekt. The Human Regenerative Ma
Huntington’s disease (HD) is an inherited progressive neurodegenerative disorder caused by an expand...
The discovery of adult neurogenesis and of stem cells in the brain has changed our view of the matur...
Adult neurogenesis is restricted to two distinct areas of the mammalian brain: the olfactory bulb (O...
Neurons are added throughout life in the hippocampus and olfactory bulb in most mammals, although hu...
International audience: In most mammals, neurons are added throughout life in the hippocampus and ol...
SummaryIn most mammals, neurons are added throughout life in the hippocampus and olfactory bulb. One...
In the adult brain, new neurons are produced in two “canonical” regions: the hippocampus and the olf...
The phenomenon of adult neurogenesis is now an accepted occurrence in mammals and also in humans. At...
Adult neurogenesis is the development of new neurons in the adult brain. In mammals, physiological a...
Abstract Background Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder li...
Abstract Background Prevailing...
<p>New neurons are indicated in green. (A) Neuroblasts that are generated in the subventricular zone...
Huntington's disease (HD) is an inherited progressive neurodegenerative disorder caused by an expand...
Huntington's disease (HD) is an inherited progressive neurodegenerative disorder caused by an expand...
Neurogenesis is the process by which cells divide, migrate, and subsequently differentiate into a ne...
Huntington’s disease (HD) is an inherited progressive neurodegenerative disorder caused by an expand...
The discovery of adult neurogenesis and of stem cells in the brain has changed our view of the matur...
Adult neurogenesis is restricted to two distinct areas of the mammalian brain: the olfactory bulb (O...
Neurons are added throughout life in the hippocampus and olfactory bulb in most mammals, although hu...
International audience: In most mammals, neurons are added throughout life in the hippocampus and ol...
SummaryIn most mammals, neurons are added throughout life in the hippocampus and olfactory bulb. One...
In the adult brain, new neurons are produced in two “canonical” regions: the hippocampus and the olf...
The phenomenon of adult neurogenesis is now an accepted occurrence in mammals and also in humans. At...
Adult neurogenesis is the development of new neurons in the adult brain. In mammals, physiological a...
Abstract Background Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder li...
Abstract Background Prevailing...
<p>New neurons are indicated in green. (A) Neuroblasts that are generated in the subventricular zone...
Huntington's disease (HD) is an inherited progressive neurodegenerative disorder caused by an expand...
Huntington's disease (HD) is an inherited progressive neurodegenerative disorder caused by an expand...
Neurogenesis is the process by which cells divide, migrate, and subsequently differentiate into a ne...
Huntington’s disease (HD) is an inherited progressive neurodegenerative disorder caused by an expand...
The discovery of adult neurogenesis and of stem cells in the brain has changed our view of the matur...
Adult neurogenesis is restricted to two distinct areas of the mammalian brain: the olfactory bulb (O...