Add to ORKGAltres ajuts: This work was supported by the the Cellex Foundation; and La Caixa Banking Foundation (LCF/PR/GN18/51140001).Effective anticancer immunotherapy treatments constitute a qualitative leap in cancer management. Nonetheless, not all patients benefit from such therapies because they fail to achieve complete responses, suffer frequent relapses, or develop potentially life-threatening toxicities. Epigenomic signatures in immune and cancer cells appear to be accurate and promising predictors of patient outcomes with immunotherapy. In addition, combined treatments with epigenetic drugs can exploit the dynamic nature of epigenetic changes to potentially modulate responses to immunotherapy. Candidate epigenetic biomarkers may provide a ra...
International audienceImmunogenic cell death (ICD) activates both innate and adaptive arms of the im...
There is great interest in developing efficient therapeutic cancer vaccines, as this type of therapy...
In 2018, the Nobel Prize in medicine was awarded to James P. Allison and Tasuku Honjo for their work...
Altres ajuts: This work was supported by the the Cellex Foundation; and La Caixa Banking Foundation ...
Immunotherapy has brought new hope for cancer patients in recent times. However, despite the promisi...
Recently, immunotherapeutic approaches have shown impressive responses in a subset of cancer patient...
The efficacy of cancer immunotherapy relies on the ability of the host immune system to recognise th...
Immune surveillance should be directed to suppress tumor development and progression, involving a ba...
Epigenetic alterations play a pivotal role in cancer development and progression. Pharmacologic reve...
Epigenetic mechanisms are processes that affect gene expression and cellular functions without invol...
Epigenetic regulation allows heritably modulating gene expression profiles without modifying the pri...
Continuously improving knowledge of the fine mechanisms regulating cross-talk between immune cells, ...
Cancer cells are under the surveillance of the host immune system. Nevertheless, a number of immunos...
The efficacy of cancer immunotherapy relies on the ability of the host immune system to recognise th...
Checkpoint inhibitor therapy constitutes a promising cancer treatment strategy that targets the immu...
International audienceImmunogenic cell death (ICD) activates both innate and adaptive arms of the im...
There is great interest in developing efficient therapeutic cancer vaccines, as this type of therapy...
In 2018, the Nobel Prize in medicine was awarded to James P. Allison and Tasuku Honjo for their work...
Altres ajuts: This work was supported by the the Cellex Foundation; and La Caixa Banking Foundation ...
Immunotherapy has brought new hope for cancer patients in recent times. However, despite the promisi...
Recently, immunotherapeutic approaches have shown impressive responses in a subset of cancer patient...
The efficacy of cancer immunotherapy relies on the ability of the host immune system to recognise th...
Immune surveillance should be directed to suppress tumor development and progression, involving a ba...
Epigenetic alterations play a pivotal role in cancer development and progression. Pharmacologic reve...
Epigenetic mechanisms are processes that affect gene expression and cellular functions without invol...
Epigenetic regulation allows heritably modulating gene expression profiles without modifying the pri...
Continuously improving knowledge of the fine mechanisms regulating cross-talk between immune cells, ...
Cancer cells are under the surveillance of the host immune system. Nevertheless, a number of immunos...
The efficacy of cancer immunotherapy relies on the ability of the host immune system to recognise th...
Checkpoint inhibitor therapy constitutes a promising cancer treatment strategy that targets the immu...
International audienceImmunogenic cell death (ICD) activates both innate and adaptive arms of the im...
There is great interest in developing efficient therapeutic cancer vaccines, as this type of therapy...
In 2018, the Nobel Prize in medicine was awarded to James P. Allison and Tasuku Honjo for their work...