Suhi ekstrakt plodova sikavice (Silybum marianum (L.) Gaertn.) - terapeutik jetre

The milk thistle, Silybum marianum (L.) Gaertn. (= Carduus marianus L.) belongs to the Asteraceae family. The history of this medicinal plant is going back to· the time of the birth of Christ. It's fruits, Fructus Cardui Mariae, commonly known as seeds, were formerly employed as a herbal remedy, while nowdays they or their products in effective dosage are recognized as a therapeutic agent. Wagner et al. (1968) were found in fruits of the milk thistle a group of flavonoid compounds. These compounds were given the name silymarin. Further studies showed that silymarin consists of three isomeric compounds: silibinin, silidianin and silicristin (molecular formula: C,){,.0,., MW 482.45) The positive effect of silymarin on elevated serum enzyme levels - an indication of parenchymal damage in patients with chronic liver diseases -has been clearly apparent in various nonblind controlled trials. Indicatons of silymarin: toxic liver damage, for supportive treatment in chronic inflammatory liver diseases and cirrhosis