Deprotonation of Benzylic Ethers Using a Hindered Phosphazene Base. A Synthesis of Benzofurans from Ortho-Substituted Benzaldehydes
- Kraus, George A.
- Zhang, Ning
- Verkade, John G.
- Nagarajan, Muthukaman
- Kisanga, Philip B.
Publication date
July 2000
DOI Publisher
Iowa State University Digital Repository ISSN
1523-7060 Language
English Citation count (estimate)
47Abstract
The hindered nonionic phosphazene base P4-t-Bu efficiently deprotonates o-arylmethoxy benzaldehydes, leading to a direct synthesis of benzofurans. Strong ionic bases such as LDA, LiTMP, and KH failed
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