HEV inactivation assessment using viable virus

Hepatitis E is an acute icteric hepatitis caused by hepatitis E virus (HEV). HEV is transmitted by water supplies in developing countries. Recently, HEV contamination in consumption water was also observed in a developed country (France). HEV is detected in pigs and several other animal species (e.g. wild boars and deer) and it is strongly suspected to be zoonotic, HEV has also been detected in the pork production chain: in a study conducted in a grocery in the USA 11% of livers tested were HEV positive and similar data have been observed in Europe also