Identifying the genetic factors that underlie complex traits is central to understanding the mechanistic underpinnings of evolution. Cave-dwelling Astyanax mexicanus populations are well adapted to subterranean life and many populations appear to have evolved troglomorphic traits independently, while the surface-dwelling populations can be used as a proxy for the ancestral form. Here we present a high-resolution, chromosome-level surface fish genome, enabling the first genome-wide comparison between surface fish and cavefish populations. Using this resource, we performed quantitative trait locus (QTL) mapping analyses and found new candidate genes for eye loss such as dusp26. We used CRISPR gene editing in A. mexicanus to confirm the essent...
International audienceAstyanax mexicanus, a teleost species with surface dwelling (surface fish) and...
International audienceAstyanax mexicanus, a teleost species with surface dwelling (surface fish) and...
Dissertation presented to obtain the Ph.D. degree in Biology at the Instituto de Tecnologia Química ...
Identifying the genetic factors that underlie complex traits is central to understanding the mechani...
Identifying the genetic factors that underlie complex traits is central to understanding the mechani...
Identifying the genetic factors that underlie complex traits is central to understanding the mechani...
International audienceNatural populations subjected to strong environmental selection pressures offe...
International audienceNatural populations subjected to strong environmental selection pressures offe...
<div><p>Numerous organisms around the globe have successfully adapted to subterranean environments. ...
International audienceNatural populations subjected to strong environmental selection pressures offe...
Natural populations subjected to strong environmental selection pressures offer a window into the ge...
International audienceNatural populations subjected to strong environmental selection pressures offe...
Natural populations subjected to strong environmental selection pressures offer a window into the ge...
Astyanax mexicanus, a teleost species with surface dwelling (surface fish) and cave adapted (cavefis...
Astyanax mexicanus, a teleost species with surface dwelling (surface fish) and cave adapted (cavefis...
International audienceAstyanax mexicanus, a teleost species with surface dwelling (surface fish) and...
International audienceAstyanax mexicanus, a teleost species with surface dwelling (surface fish) and...
Dissertation presented to obtain the Ph.D. degree in Biology at the Instituto de Tecnologia Química ...
Identifying the genetic factors that underlie complex traits is central to understanding the mechani...
Identifying the genetic factors that underlie complex traits is central to understanding the mechani...
Identifying the genetic factors that underlie complex traits is central to understanding the mechani...
International audienceNatural populations subjected to strong environmental selection pressures offe...
International audienceNatural populations subjected to strong environmental selection pressures offe...
<div><p>Numerous organisms around the globe have successfully adapted to subterranean environments. ...
International audienceNatural populations subjected to strong environmental selection pressures offe...
Natural populations subjected to strong environmental selection pressures offer a window into the ge...
International audienceNatural populations subjected to strong environmental selection pressures offe...
Natural populations subjected to strong environmental selection pressures offer a window into the ge...
Astyanax mexicanus, a teleost species with surface dwelling (surface fish) and cave adapted (cavefis...
Astyanax mexicanus, a teleost species with surface dwelling (surface fish) and cave adapted (cavefis...
International audienceAstyanax mexicanus, a teleost species with surface dwelling (surface fish) and...
International audienceAstyanax mexicanus, a teleost species with surface dwelling (surface fish) and...
Dissertation presented to obtain the Ph.D. degree in Biology at the Instituto de Tecnologia Química ...