Add to ORKGThis thesis describes a variety of asymmetric cis- and trans-platinum(II) complexes. The major aim of this research has been the design of complexes with high antitumor activity that may overcome cisplatin resistance, and to establish a comparison between complexes with both geometries. These new type of asymmetric platinum complexes contain in all cases the iPram ligand and in addition either aliphatic amines or azole ligands. Furthermore, a strong emphasis on asymmetric trans-Pt(II) complexes with azole ligands is presented in this research.Kreatech, NWOUBL - phd migration 201
Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2019, Tutor:...
The constantly observed increase in the number of cancer cases inspires research aimed at searching ...
The anti-cancer chemotherapeutic potential of novel platinum(II) complexes of salicylate derivatives...
This thesis describes a variety of asymmetric cis- and trans-platinum(II) complexes. The major aim o...
Asymmetric cis-platinum(II) complexes with isopropylamine and two different azole ligands were synth...
Wide range of dose-limiting toxicities and tumor resistance to drug are significant limitations of t...
Three new asymmetric platinum(II) complexes comprising an isopropylamine ligand trans to an azole li...
The research of new platinum drugs active towards cisplatin refractory/resistant tumors has been mos...
Inspired by cisplatin, the inorganic drug discovered by Barnett Rosenberg in 1965, the research desc...
Cisplatin represents one of the most potent drugs available in the cancer chemotherapy for several s...
In this thesis new fluorescent platinum(II) compounds are presented. All these new compounds were de...
This thesis focuses on developing new platinum complexes with potential anti-cancer properties. The ...
The discovery of cisplatin (cis-Pt(NH3)2Cl2) as an antineoplastic agent has focused attention on the...
In order to compare the mechanistic properties of the antitumour-active trans platinum complex trans...
Chemotherapy is a primary source of treatment for victims of cancer, a globally prominent disease th...
Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2019, Tutor:...
The constantly observed increase in the number of cancer cases inspires research aimed at searching ...
The anti-cancer chemotherapeutic potential of novel platinum(II) complexes of salicylate derivatives...
This thesis describes a variety of asymmetric cis- and trans-platinum(II) complexes. The major aim o...
Asymmetric cis-platinum(II) complexes with isopropylamine and two different azole ligands were synth...
Wide range of dose-limiting toxicities and tumor resistance to drug are significant limitations of t...
Three new asymmetric platinum(II) complexes comprising an isopropylamine ligand trans to an azole li...
The research of new platinum drugs active towards cisplatin refractory/resistant tumors has been mos...
Inspired by cisplatin, the inorganic drug discovered by Barnett Rosenberg in 1965, the research desc...
Cisplatin represents one of the most potent drugs available in the cancer chemotherapy for several s...
In this thesis new fluorescent platinum(II) compounds are presented. All these new compounds were de...
This thesis focuses on developing new platinum complexes with potential anti-cancer properties. The ...
The discovery of cisplatin (cis-Pt(NH3)2Cl2) as an antineoplastic agent has focused attention on the...
In order to compare the mechanistic properties of the antitumour-active trans platinum complex trans...
Chemotherapy is a primary source of treatment for victims of cancer, a globally prominent disease th...
Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2019, Tutor:...
The constantly observed increase in the number of cancer cases inspires research aimed at searching ...
The anti-cancer chemotherapeutic potential of novel platinum(II) complexes of salicylate derivatives...