Cochlear imaging in the era of cochlear implantation : from silence to sound

Cochlear implants (CIs) are a well accepted treatment for hearing impaired people. In pre- and postoperative assessment of CI-candidates imaging plays an important role to analyze anatomy, rule out pathology and determine intracochlear positioning and integrity of the implant. Developments in CI-design, differences in surgical approach and broadening of treatment indications have raised new questions to radiologists, which were the subject of several studies described in this thesis. For optimal, a-traumatic positioning of a CI precise information about the inner ear anatomy is mandatory. We describe the development, validation and application of a method for 3-dimensional medical image exploration of the inner ear. This renders a tool to obtain cochlear dimensions on clinical computer tomography (CT) images. This will be useful for patientspecific implantplanning. It also shows an anatomical substrate for cochlear trauma during insertion. For postoperative imaging we studied the value of multislice-CT for optimal visualization of the implant within the cochlea. Its role to evaluate operation technique and electrode design, to study frequency mapping and to assess cochlear trauma is discussed. Moreover an international consensus for an objective cochlear framework is presented, forming a common ground for clear and easy exchange of findings in scientific and clinical studies.AB, de Nationale Hoorstichting/Sponsor Bingo Loterij, Foundation Imago, Bontius Stichting inz. Doelfonds BeeldverwerkingUBL - phd migration 201