Interferon-gamma release assays based on region of difference 1 antigens have improved diagnosis of latent tuberculosis infection (LTBI). However, these tests cannot discriminate between recently acquired infection (higher risk of progression to active tuberculosis) and remote LTBI. The objective of the present study was to evaluate the T-cell interferon-gamma responses to Mycobacterium tuberculosis DosR-regulon-encoded antigens (latency antigens) compared with QuantiFERON TB-Gold In-Tube (QFT-GIT) in subjects at different stages of tuberculosis. A total of 16 individuals with remote LTBI and 23 with recent infection were studied; 15 controls unexposed to M. tuberculosis and 50 patients with active tuberculosis and 45 with cured tuberculosi...
Discordant results between the interferon-gamma release assays (IGRAs) and tuberculin skin test (TST...
AbstractEffective control of tuberculosis (TB) includes discrimination of subjects with active TB fr...
Mycobacterium tuberculosis is estimated to infect 80 to 100 million people annually, the majority of...
Interferon-gamma-release assays based on RD1 antigens have improved diagnosis of latent tuberculosis...
International audienceTuberculin skin test (TST) and IFN-γ release assays are currently used to dete...
Background: T-cell responses against dormancy-, resuscitation-, and reactivation-associated antigens...
BACKGROUND: T-cell responses against dormancy-, resuscitation-, and reactivation-associated antigens...
-specific immunity in humans have focused on the periphery rather than the site of active infection,...
The majority of individuals infected with Mycobacterium tuberculosis achieve lifelong immune contain...
RATIONALE Due to the invasive nature of the procedures involved, most studies of Mycobacterium tuber...
The majority of individuals infected with Mycobacterium tuberculosis achieve lifelong immune contain...
Abstract Background Interferon-gamma (IFN-γ) release assays (IGRAs) were designed to detect latent t...
Mycobacterium tuberculosis Resuscitation-promoting factor proteins (Rpf) induce stronger T-cell resp...
IFN-γ release assays (IGRAs) are better indicators of Mycobacterium tuberculosis infection than the ...
AbstractIFN-γ release assays (IGRAs) are better indicators of Mycobacterium tuberculosis infection t...
Discordant results between the interferon-gamma release assays (IGRAs) and tuberculin skin test (TST...
AbstractEffective control of tuberculosis (TB) includes discrimination of subjects with active TB fr...
Mycobacterium tuberculosis is estimated to infect 80 to 100 million people annually, the majority of...
Interferon-gamma-release assays based on RD1 antigens have improved diagnosis of latent tuberculosis...
International audienceTuberculin skin test (TST) and IFN-γ release assays are currently used to dete...
Background: T-cell responses against dormancy-, resuscitation-, and reactivation-associated antigens...
BACKGROUND: T-cell responses against dormancy-, resuscitation-, and reactivation-associated antigens...
-specific immunity in humans have focused on the periphery rather than the site of active infection,...
The majority of individuals infected with Mycobacterium tuberculosis achieve lifelong immune contain...
RATIONALE Due to the invasive nature of the procedures involved, most studies of Mycobacterium tuber...
The majority of individuals infected with Mycobacterium tuberculosis achieve lifelong immune contain...
Abstract Background Interferon-gamma (IFN-γ) release assays (IGRAs) were designed to detect latent t...
Mycobacterium tuberculosis Resuscitation-promoting factor proteins (Rpf) induce stronger T-cell resp...
IFN-γ release assays (IGRAs) are better indicators of Mycobacterium tuberculosis infection than the ...
AbstractIFN-γ release assays (IGRAs) are better indicators of Mycobacterium tuberculosis infection t...
Discordant results between the interferon-gamma release assays (IGRAs) and tuberculin skin test (TST...
AbstractEffective control of tuberculosis (TB) includes discrimination of subjects with active TB fr...
Mycobacterium tuberculosis is estimated to infect 80 to 100 million people annually, the majority of...