In summary, chapter 1 of this thesis provides a background on the demographic, biologic and cardiovascular aspects of brain aging. Chapter 2 shows that higher blood pressure is associated with lower cognitive decline in very old age. Findings of Chapter 3 indicate that higher blood pressure is associated with lower risk of stroke in very old subjects with higher degrees of disability. In chapter 4, we showed that visit-to-visit blood pressure variability might put subjects at a higher risk for accelerated brain aging. In Chapters 5 to 7, we observed that a strong association exists between a graded decrease in cardiac function and lower brain volumes and cognitive performance. In a meta-analysis (Chapter 8), we demonstrated that in patients...
Vascular risk factors are believed to be involved in dementia development by increasing risk of the ...
To access publisher's full text version of this article click on the hyperlink at the bottom of the ...
An age-related decline in cerebral blood flow (CBF) is widely acknowledged. However, uncertainty exi...
With increasing age the prevalence of hypertension rises. High blood pressur...
The overriding aim of my thesis was to study the relationship between blood pressure (BP) and cogn...
Brain function is supported by the cerebrovascular system, and changes in vascular phenotype and fun...
Brain aging, the phenomenon by which the passage of chronological time is associated with reduced br...
Cardiovascular disease is a major health problem worldwide. Accumulating evidence suggests that card...
INTRODUCTION: Understanding relationships among blood pressure (BP), cognition, and brain volume cou...
Cognitive decline is an underexposed consequence of stroke and heart disease. This dissertation reve...
Introduction: Cognitive functions play a crucial role in daily functioning. Unfortunately, some cogn...
While age has the strongest associations with the development of dementia, a myriad of modifiable ca...
textabstractThe devastating impact of the loss of cognitive abilities that often accompanies the agi...
During aging, vascular declines occur causing cerebral atrophy, and functional deteriorations. When ...
Background: Vascular disease is associated with increased risk of dementia. Vascular health worsens ...
Vascular risk factors are believed to be involved in dementia development by increasing risk of the ...
To access publisher's full text version of this article click on the hyperlink at the bottom of the ...
An age-related decline in cerebral blood flow (CBF) is widely acknowledged. However, uncertainty exi...
With increasing age the prevalence of hypertension rises. High blood pressur...
The overriding aim of my thesis was to study the relationship between blood pressure (BP) and cogn...
Brain function is supported by the cerebrovascular system, and changes in vascular phenotype and fun...
Brain aging, the phenomenon by which the passage of chronological time is associated with reduced br...
Cardiovascular disease is a major health problem worldwide. Accumulating evidence suggests that card...
INTRODUCTION: Understanding relationships among blood pressure (BP), cognition, and brain volume cou...
Cognitive decline is an underexposed consequence of stroke and heart disease. This dissertation reve...
Introduction: Cognitive functions play a crucial role in daily functioning. Unfortunately, some cogn...
While age has the strongest associations with the development of dementia, a myriad of modifiable ca...
textabstractThe devastating impact of the loss of cognitive abilities that often accompanies the agi...
During aging, vascular declines occur causing cerebral atrophy, and functional deteriorations. When ...
Background: Vascular disease is associated with increased risk of dementia. Vascular health worsens ...
Vascular risk factors are believed to be involved in dementia development by increasing risk of the ...
To access publisher's full text version of this article click on the hyperlink at the bottom of the ...
An age-related decline in cerebral blood flow (CBF) is widely acknowledged. However, uncertainty exi...