Add to ORKGThis thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.Bio-organic Synthesi
Internalization of peptides by antigen presenting cells is crucial for the initiation of the adaptiv...
Immunotherapy is deemed one of the most powerful therapeutic approaches to treat cancer. However, li...
Internalization of peptides by antigen presenting cells is crucial for the initiation of the adaptiv...
Dendritic cells (DC) are unique antigen presenting cells which play a major role in antigen presenta...
Dendritic cells (DCs) are armed with a multitude of Pattern Recognition Receptors (PRRs) to recogniz...
Cells express a large array of membrane receptors on their surface that function as a communication ...
Immunotherapy is deemed one of the most powerful therapeutic approaches to treat cancer. However, li...
Langerhans cells (LCs) are antigen-presenting cells that reside in the skin. They uniquely express h...
Macrophages (MΦ) are involved in a number of pathological conditions, such as HIV infection/AIDS, tu...
The mannose receptor (MR) is an important component of the immune system and understanding the struc...
Present on the surface of antigen presenting cells (APCs), the mannose receptor (MR) has long been r...
The aim of the present study is preparation of mannosylated liposomes with built-in small molecule i...
BACKGROUND. An experimental approach for improving vaccine efficacy involves targeting antigens to...
Antigen mannosylation has been shown to be an effective approach to potentiate antigen immunogenicit...
Benzene-1,3,5-tricarboxamide (BTA) glyco-monomers containing one, two or three mannose units are syn...
Internalization of peptides by antigen presenting cells is crucial for the initiation of the adaptiv...
Immunotherapy is deemed one of the most powerful therapeutic approaches to treat cancer. However, li...
Internalization of peptides by antigen presenting cells is crucial for the initiation of the adaptiv...
Dendritic cells (DC) are unique antigen presenting cells which play a major role in antigen presenta...
Dendritic cells (DCs) are armed with a multitude of Pattern Recognition Receptors (PRRs) to recogniz...
Cells express a large array of membrane receptors on their surface that function as a communication ...
Immunotherapy is deemed one of the most powerful therapeutic approaches to treat cancer. However, li...
Langerhans cells (LCs) are antigen-presenting cells that reside in the skin. They uniquely express h...
Macrophages (MΦ) are involved in a number of pathological conditions, such as HIV infection/AIDS, tu...
The mannose receptor (MR) is an important component of the immune system and understanding the struc...
Present on the surface of antigen presenting cells (APCs), the mannose receptor (MR) has long been r...
The aim of the present study is preparation of mannosylated liposomes with built-in small molecule i...
BACKGROUND. An experimental approach for improving vaccine efficacy involves targeting antigens to...
Antigen mannosylation has been shown to be an effective approach to potentiate antigen immunogenicit...
Benzene-1,3,5-tricarboxamide (BTA) glyco-monomers containing one, two or three mannose units are syn...
Internalization of peptides by antigen presenting cells is crucial for the initiation of the adaptiv...
Immunotherapy is deemed one of the most powerful therapeutic approaches to treat cancer. However, li...
Internalization of peptides by antigen presenting cells is crucial for the initiation of the adaptiv...