Add to ORKGThis thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular polysaccharide of Streptococcus pneumonia (Sp1). All the synthesized fragments were equipped with a spacer at the reducing end for further conjugation with proteins or active small molecules to explore the mechanisms of carbohydrate-based vaccines in immune responses and to develop novel vaccines. To investigate the structure-activity relationship, several fragments of each polysaccharide were assembled varying in length. Bio-organic Synthes...
The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacte...
Already for more than half a century, scientists have made efforts to develop vaccines that prevent ...
The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacte...
In the last decade glycoimmunology, a new research field dealing with the specific interactions of c...
Group B Streptococcus (GBS) is a Gram-positive bacterium and the most common cause of neonatal blood...
Group B Streptococcus (GBS) is a major neonatal pathogen and a leading cause of infant mortality wor...
This thesis describes the synthesis of various teichoic acid (TA)-fragments, capsular polysaccharide...
This MSc thesis is composed of two investigations: the structure of the capsular polysaccharide expr...
We recently mapped the structural epitope of the capsular polysaccharide from type III Group B Strep...
Group A Streptococcus (GAS) is responsible for superficial infections, systemic disease, and autoimm...
Glycopolymers are found surrounding the outer layer of many bacterial species. The first uses as imm...
This thesis describes chemical synthesis of carbohydrates and glycopeptides useful in studies of bio...
Carbohydrates in the form of capsular polysaccharides are the major components on the surface of bac...
Streptococcus pneumoniae (SP) is a common human pathogen associated with a broad spectrum of disease...
During the last decade there has been a growing interest in glycoimmunology, a relatively new resear...
The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacte...
Already for more than half a century, scientists have made efforts to develop vaccines that prevent ...
The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacte...
In the last decade glycoimmunology, a new research field dealing with the specific interactions of c...
Group B Streptococcus (GBS) is a Gram-positive bacterium and the most common cause of neonatal blood...
Group B Streptococcus (GBS) is a major neonatal pathogen and a leading cause of infant mortality wor...
This thesis describes the synthesis of various teichoic acid (TA)-fragments, capsular polysaccharide...
This MSc thesis is composed of two investigations: the structure of the capsular polysaccharide expr...
We recently mapped the structural epitope of the capsular polysaccharide from type III Group B Strep...
Group A Streptococcus (GAS) is responsible for superficial infections, systemic disease, and autoimm...
Glycopolymers are found surrounding the outer layer of many bacterial species. The first uses as imm...
This thesis describes chemical synthesis of carbohydrates and glycopeptides useful in studies of bio...
Carbohydrates in the form of capsular polysaccharides are the major components on the surface of bac...
Streptococcus pneumoniae (SP) is a common human pathogen associated with a broad spectrum of disease...
During the last decade there has been a growing interest in glycoimmunology, a relatively new resear...
The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacte...
Already for more than half a century, scientists have made efforts to develop vaccines that prevent ...
The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacte...