High throughput extracellular vesicle sorting using electrokinetic deterministic lateral displacement

We present a microfluidic device that can sort nanosized extracellular vesicles (EVs) based on electrokinetics and Deterministic Lateral Displacement (DLD). The device is made from PDMS using standard soft-lithography, can separate particles down to 200 nm, and what is more, can achieve almost two orders of magnitude higher throughput than an otherwise single electrokinetic DLD device