Add to ORKGComunicación presentada en New Horizons in Genomics symposium, celebrado en modalidad virtual del del 10 al 11 de septiembre de 2020.Cytosine-5 methylation is one of the best characterized epigenetic modification found in DNA. However, the cellular and molecular functions of the same modified nucleobase in RNA remain unclear. I have recently shown the physiological role of 5-methylcytosine (m C) in transfer RNA in growth and self-renewal regulation and how alterations of this post-transcriptional modification contribute to human diseases including cancer. Now, our studies reveal that aberrant expression of other RNA modifying proteins may confer an advantage to cancer cells
[eng] The general aim of this thesis is to identify and characterize if there are DNA methylation pa...
The modified base 5-methylcytosine (m5C) is well studied in DNA, but investigations of its prevalenc...
Vast emerging evidences are linking the base modifications and determination of stem cell fate such ...
Trabajo presentado en el ciclo de conferencias CIC, celebrado en modalidad virtual el 17 de junio de...
5-methylcytosine (m5C) is an abundant RNA modification that’s presence is reported in a wide v...
[eng] Transfer RNAs (tRNAs) are essential molecules that allow the translation of the genetic code i...
The recent advent of high-throughput sequencing technologies coupled with RNA modifications detectio...
The human cytoplasmatic pool of tRNA for the 20 proteinogenic amino acids and selenocysteine is comp...
Chemical modifications have been studied as key modulators of RNA biology for over 50 years. There a...
Recently, covalent modifications of RNA, such as methylation, have emerged as key regulators of all ...
Over the last five decades more than 100 types of RNA modifications have been identified in organism...
Abstract Background 5-Methylcytosine (m5C) is a reversible modification to both DNA and various cell...
The field of epitranscriptomics encompasses the study of post-transcriptional RNA modifications and ...
Modified nucleosides play an important role in RNA function and have been identified in multiple RNA...
Abstract RNA methylation has emerged as a fundamental process in epigenetic regulation...
[eng] The general aim of this thesis is to identify and characterize if there are DNA methylation pa...
The modified base 5-methylcytosine (m5C) is well studied in DNA, but investigations of its prevalenc...
Vast emerging evidences are linking the base modifications and determination of stem cell fate such ...
Trabajo presentado en el ciclo de conferencias CIC, celebrado en modalidad virtual el 17 de junio de...
5-methylcytosine (m5C) is an abundant RNA modification that’s presence is reported in a wide v...
[eng] Transfer RNAs (tRNAs) are essential molecules that allow the translation of the genetic code i...
The recent advent of high-throughput sequencing technologies coupled with RNA modifications detectio...
The human cytoplasmatic pool of tRNA for the 20 proteinogenic amino acids and selenocysteine is comp...
Chemical modifications have been studied as key modulators of RNA biology for over 50 years. There a...
Recently, covalent modifications of RNA, such as methylation, have emerged as key regulators of all ...
Over the last five decades more than 100 types of RNA modifications have been identified in organism...
Abstract Background 5-Methylcytosine (m5C) is a reversible modification to both DNA and various cell...
The field of epitranscriptomics encompasses the study of post-transcriptional RNA modifications and ...
Modified nucleosides play an important role in RNA function and have been identified in multiple RNA...
Abstract RNA methylation has emerged as a fundamental process in epigenetic regulation...
[eng] The general aim of this thesis is to identify and characterize if there are DNA methylation pa...
The modified base 5-methylcytosine (m5C) is well studied in DNA, but investigations of its prevalenc...
Vast emerging evidences are linking the base modifications and determination of stem cell fate such ...