Syntheses of some new porphyrin photosensitizers for photodynamic therapy

© 1990 SPIE. Syntheses and chemical characterization of a number of new porphyrin-derived sensitizers, related to Photofrin-II and otherwise, are described. The major thrust of our more recent work centers on preparation of porphyrin oligomers linked by ester, ether, or carbon-carbon bonds, as well as photosensitizers with long-wavelength absorbance. Where appropriate, PDT activity is briefly mentioned