Treatment of zinc(II) deuteroporphyrin-IX dimethyl ester with thallium(III) trifluoroacetate, followed by acid treatment, affords the four isomeric oxophlorins (oxyporphyrins) in a reaction which is considerably more easy to control than the traditional method involving coupled oxidation of the corresponding hemin. The oxophlorins, obtained in very high yield, are chromatographically separable on a preparative scale. Using nuclear Overhauser enhancement and NMR spin-decoupling experiments, the isomeric deuterobiliverdins and meso-acetoxyporphyrins derived from the isomerically pure oxophlorins are assigned definitive structures. This work suggests that the original assignments of the β- and δ- deuterobiliverdins, made on the basis of coup...
This dissertation describes the design and synthesis of a number of porphyrin derivatives designed t...
Mesohemin (1), deuterohemin (2), protohemin (3), 6,7-dipropylmesohemin (22), 1-(2-carboxyethyl)-meso...
Base-catalysed dehydrohalogenation of a 3,18-bis(2-chloroethyl)biliverdin 1 affords a novel 3-vinylb...
Treatment of hematoporphyrin IX dimethyl ester (7) with tetrapropylammonium perruthenate (Prn4N)(Ru0...
Hydroxyisooxophlorin is an oxidatively degraded porphyrin that contains one carbonyl carbon, one hyd...
Syntheses of novel 15-substituted-oxophlorins via the MacDonald condensation of diformyl-dipyrroketo...
Administration of phenylhydrazine to rabbits resulted in the denaturation of hemoglobins in erythroc...
In connection with proposed 19F NMR studies of reconstituted fluorine-substituted heme proteins, syn...
Treatment of meso-substituted metalloporphyrins [meso -substituent = OCOCF3, OCOCH3, OMe, CHO, CN, C...
Treatment of magnesium or zinc porphyrins with thallium(III) trifluoroacetate, followed by an acidic...
In order to settle the precise identity of certain resonances in the paramagnetic n.m.r. spectra of ...
Zinc(II) porphyrins bearing unsubstituted β positions can be mercurated at the β position and at an ...
In order to aid in elucidation of the structure of the active components in hematoporphyrin derivati...
Zinc(II) δ-trifluoroacetoxypheophorbides (5, 10) undergo macrocyclic ring cleavage, via zinc(II) oxo...
Treatment of porphyrins with thallium(III) trifluoroacetate in the presence of trifluoroacetic acid ...
This dissertation describes the design and synthesis of a number of porphyrin derivatives designed t...
Mesohemin (1), deuterohemin (2), protohemin (3), 6,7-dipropylmesohemin (22), 1-(2-carboxyethyl)-meso...
Base-catalysed dehydrohalogenation of a 3,18-bis(2-chloroethyl)biliverdin 1 affords a novel 3-vinylb...
Treatment of hematoporphyrin IX dimethyl ester (7) with tetrapropylammonium perruthenate (Prn4N)(Ru0...
Hydroxyisooxophlorin is an oxidatively degraded porphyrin that contains one carbonyl carbon, one hyd...
Syntheses of novel 15-substituted-oxophlorins via the MacDonald condensation of diformyl-dipyrroketo...
Administration of phenylhydrazine to rabbits resulted in the denaturation of hemoglobins in erythroc...
In connection with proposed 19F NMR studies of reconstituted fluorine-substituted heme proteins, syn...
Treatment of meso-substituted metalloporphyrins [meso -substituent = OCOCF3, OCOCH3, OMe, CHO, CN, C...
Treatment of magnesium or zinc porphyrins with thallium(III) trifluoroacetate, followed by an acidic...
In order to settle the precise identity of certain resonances in the paramagnetic n.m.r. spectra of ...
Zinc(II) porphyrins bearing unsubstituted β positions can be mercurated at the β position and at an ...
In order to aid in elucidation of the structure of the active components in hematoporphyrin derivati...
Zinc(II) δ-trifluoroacetoxypheophorbides (5, 10) undergo macrocyclic ring cleavage, via zinc(II) oxo...
Treatment of porphyrins with thallium(III) trifluoroacetate in the presence of trifluoroacetic acid ...
This dissertation describes the design and synthesis of a number of porphyrin derivatives designed t...
Mesohemin (1), deuterohemin (2), protohemin (3), 6,7-dipropylmesohemin (22), 1-(2-carboxyethyl)-meso...
Base-catalysed dehydrohalogenation of a 3,18-bis(2-chloroethyl)biliverdin 1 affords a novel 3-vinylb...